The efficacy of volumetric computed tomography histogram analysis in adrenal masses

Aims: The rate of adrenal mass detection has increased due to the development imaging modalities. It is vital differentiate benign adenomas from other masses in order establish whether an active management strategy essential. Volumetric CT histogram analysis calculates percentage covered pixels negative attenuation region. goal this research was evaluate diagnostic utility volume for tumors confirmed histopathologically as well ideal slice thickness between and malignant lesions with a density greater than 10 Hounsfield units (HU).
 Methods: analyzed images 127 individuals 136 that were verified after resection (57 lipid-poor adenomas, 21 pheochromocytomas, 47 metastases, 11 adrenocortical carcinomas). For imaging, 40-row MDCT device (Siemens Medical Solution, Erlanger, Germany) utilized. 1 mm 5 unenhanced obtained. Two separate radiologists manually assessed (HU) masses. 5th 95th percentiles HU values, minimum, mean, maximum skewness, kurtosis, variance, calculated. Interobserver agreement determined by means interclass correlation coefficient (ICC).
 Results: parameters group all higher those group, difference more significant thickness. HUmin (P=0.007), HUmean HUmedian (P